What is the cannabinoid receptor-2 (CB2). Similar to CB1, CB2 is a G protein receptor that serves as a target for endocannabinoids and phytocannabinoids. These CB2 receptors are primarily immunomodulatory and anti-inflammatory. They are expressed on the cell membranes of B cells, T cells and macrophages. When signaled, CB2 receptors are generally inhibitory to immune cell activation. Expression of CB2Read more
Tag Archives: CD1
UK Government Letter of Guidance On Cannabis Based Products for Medicinal Use 31/10/18. Prior to legalization on 1st November 2018
A fantastic podcast on the topicRead more
SOURCE: https://www.newcannabisventures.com/dea-green-lights-epidiolex-as-first-cannabis- September 27, 2018 at 9:22 am Breaking News by Alan Brochstein, CFA The DEA has given Epidiolex, the CBD-based pharmaceutical derived from cannabis that was approved by the FDA for the treatment of rare forms of epilepsy in June, Schedule V status according to the Office of the Federal Register. The developer of the pharmaceutical, GW Pharma (NASDAQ:Read more
Detailed analysis of selected pathological conditions and effects of cannabis and its derivatives with weaker clinical evidence and a strong theoretical basis favoring effectiveness. With reference to Parkinson’s disease.
A short quote from the .pdf (a link to the detailed analysis is at the end of this post). ” Parkinson’s disease This disease, whose symptoms especially include a decrease in the number of dopaminergic neurons in the basal ganglia (“BG”), is, due to its high prevalence (especially among older patients) and simultaneous existence of endocannabinoid receptors in the BGRead more
DR. DUSTIN SULAK March 12, 2018 (Nastasic/istock) Cannabidiol (CBD) is an exciting focus of medical research, popular media, and legislation related to cannabis. Its presence is becoming ubiquitous on the shelves of health food stores and search engine results for numerous medical conditions, but don’t believe everything you hear. While CBD is an incredibly safe and therapeutic component of cannabis, thereRead more